Sealed Glass Ampoules

An ampoule is a small glass container that is sealed by melting its neck closed, so the contents are hermetically protected with no cap, liner or thread to leak or let air in. Borrowed from pharmaceutical practice, it has become a premium skincare format for unstable, high-potency actives that must stay pristine until use.

Because each ampoule is a single dose opened fresh, there is no in-use oxidation or contamination — which is the whole selling point for ingredients like vitamin C, retinol and freeze-dried actives that degrade once exposed to air.

Concentrated serums, freeze-dried and fresh actives, vitamin C and retinol shots, intensive treatment courses, post-procedure skincare, hair and scalp ampoules, spa and clinic protocols, and single-dose samples. Often sold as a timed course of daily ampoules.

A small glass body drawn to a narrow neck that is flame-sealed after filling. A one-point-cut (OPC) score or a color-break ring lets the user snap the tip cleanly by hand without a file. Color-code rings on the neck identify variants. Type I borosilicate is used for the most sensitive or reactive formulas.

Ampoules are filled and then flame-sealed, often under inert gas for oxygen-sensitive actives; sealing quality is critical, as a poor seal defeats the format. Users snap the scored neck to open, so packaging should warn about the glass tip and, ideally, include an opening aid. Because they are single-use, there is no resealing — the dose is meant to be used at once.

Ampoules are usually formed from glass tubing on converting machines that shape the body and neck, then scored or ringed for opening. After filling, the neck is flame-sealed (tip-seal or pull-seal). Seal integrity and the snap-open feature are checked, and borosilicate grades are used where chemical resistance is required.