Overview
Inside almost every closure is a small component that does the actual sealing. Silicone O-rings and PTFE-faced liners are the parts to specify when an ordinary foam or PE liner is not enough. A PTFE facing is about as chemically inert as a sealing surface gets: it stands up to solvents, acids, oils and high-alcohol products that attack standard liners.
Silicone O-rings add a compressible, resilient seal that holds across a wide temperature range, which is why they are used in food, pharmaceutical and laboratory assemblies.